28 March 2024>: Clinical Research
Prognostic Significance of Neutrophil-to-Lymphocyte Ratio in Predicting Complete Pathological Response in Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy
Mustafa Karaca 1ACDEF* , Ece Salim 2ABDEF , Mustafa Serkan Alemdar 3BDEF , Özge Deniz Karaca 2BEF , Mustafa Özgür Arıcı 3BDEFDOI: 10.12659/MSM.943750
Med Sci Monit 2024; 30:e943750
Table 1 Demographic and clinical characteristics of the patients.
Variables | Total patients (n=187) |
---|---|
Age (years), mean±SD | 64.59±11.19 |
Gender, n (%) | |
Male | 123 (65.8) |
Female | 64 (34.2) |
Comorbid disease, n (%) | 75 (40.1) |
Diabetes mellitus | 37 (19.8) |
Hypertension | 34 (18.2) |
Ulcerative colitis | 2 (1.1) |
Coronary artery disease | 2 (1.1) |
Chemotherapy agent, n (%) | |
Capecitabine | 96 (51.3) |
5-FU | 91 (48.7) |
Type of surgery, n (%) | |
LAR | 154 (82.4) |
MILES operation | 33 (17.6) |
Pathological response, n (%) | |
Complete response | 34 (18.2) |
Near-complete response | 61 (32.6) |
Partial response | 68 (36.4) |
No response | 24 (12.8) |
5-FU – 5-Fluorouracil; LAR – low anterior resection. |