08 December 2022: Clinical Research
Predicting Chemotherapy Resistance in Gestational Trophoblastic Neoplasia: Ratio of Neutrophils, Lymphocytes, Monocytes, and Platelets
Gatot Nyarumenteng Adhipurnawan Winarno 1ABCDEF* , Ayu Insafi Mulyantari 1ABCDEF , Andi Kurniadi 1BD , Dodi Suardi 1BD , Zulvayanti Zulvayanti 1BD , Nurvita Trianasari 2CDOI: 10.12659/MSM.938499
Med Sci Monit 2022; 28:e938499
Table 1 Comparison of characteristics and clinical features of study patients with chemotherapy outcome in GTN patients at Hasan Sadikin Hospital.
| Characteristics | GTN (N=129) | P value | |
|---|---|---|---|
| ChemoresistanceN=68 | ChemosensitiveN=61 | ||
| Mean±Std | 34.16±9.220 | 35.64±9.879 | |
| Median | 34.00 | 35.00 | |
| Range (min-max) | 19.00–50.00 | 19.00–57.00 | |
| 0.608 | |||
| I | 30 (93.8%) | 33 (97.1%) | |
| II | 0 (0.0%) | 0 (0.0%) | |
| III | 2 (6.3%) | 1 (2.9%) | |
| IV | 0 (0.0%) | 0 (0.0%) | |
| 0.621 | |||
| I | 17 (58.6%) | 23 (67.6%) | |
| II | 2 (6.9%) | 3 (8.8%) | |
| III | 9 (31.0%) | 8 (23.5%) | |
| IV | 1 (3.4%) | 0 (0.0%) | |
| 0.320 | |||
| Mean±Std | 219655.32±333380.352 | 126802.54±278576.042 | |
| Median | 71421.85 | 3962.50 | |
| Mean±Std | 469898.53±434290.386 | 420471.80±481433.208 | |
| Median | 284264.00 | 65344.00 | |
| ≤6 (low risk) | 34 (50.0%) | 32 (52.5%) | |
| ≥7 (high risk) | 34 (50.0%) | 29 (47.5%) | |
| 2 | 2 (3.3%) | 7 (9.7%) | |
| 3 | 4 (6.6%) | 5 (6.9%) | |
| 4 | 6 (9.8%) | 12 (16.7%) | |
| 5 | 5 (8.2%) | 8 (11.1%) | |
| 6 | 15 (24.6%) | 6 (8.3%) | |
| 7 | 13 (21.3%) | 13 (18.1%) | |
| 8 | 7 (11.5%) | 10 (13.9%) | |
| 9 | 3 (4.9%) | 4 (5.6%) | |
| 10 | 4 (6.6%) | 1 (1.4%) | |
| 11 | 1 (1.6%) | 3 (4.2%) | |
| 12 | 0 (0.0%) | 2 (2.8%) | |
| 13 | 1 (1.6%) | 1 (1.4%) | |
| MTX | 33 (48.5%) | 33 (54.1%) | |
| EMACO | 35 (51.5%) | 28 (45.9%) | |