10 August 2022>: Clinical Research
A Retrospective Study from a Single Center to Identify Hematological Factors that Distinguish Between Patients with Colorectal Carcinoma and Colorectal Adenoma
Jun Huang 12AE , Pingping Xu 3BCD , Youxiang Chen 4AE*DOI: 10.12659/MSM.936745
Med Sci Monit 2022; 28:e936745
Supplementary Table 1 Proportion of missing variables and sensitivity analysis.
Characteristic | Data missing ratio (%) | After interpolation | Before interpolation | Statistics | P |
---|---|---|---|---|---|
Hb, g/L, Mean±SD | 0.12 | 125.14±24.58 | 125.15±24.59 | t=−0.010 | 0.996 |
RBC, 10/L, Mean±SD | 0.12 | 4.21±0.65 | 4.21±0.65 | t=−0.030 | 0.975 |
WBC, 10/L, M (Q, Q) | 0.12 | 5.87 (4.77, 7.34) | 5.87 (4.77, 7.34) | Z=0.034 | 0.973 |
NEUT, 10/L, M (Q, Q) | 0.12 | 3.67 (2.83, 5.15) | 3.67 (2.83, 5.15) | Z=0.033 | 0.974 |
LYM, 10/L, M (Q, Q) | 0.12 | 1.42 (1.07, 1.80) | 1.42 (1.07, 1.80) | Z=0.005 | 0.996 |
MONO, 10/L, M (Q, Q) | 0.12 | 0.35 (0.26, 0.46) | 0.35 (0.26, 0.46) | Z=0.032 | 0.975 |
PLT, 10/L, M (Q, Q) | 0.12 | 227.00 (181.00, 281.00) | 227.00 (181.00, 281.00) | Z=0.036 | 0.971 |
MPV, fL, Mean±SD | 1.40 | 10.14±1.49 | 10.13±1.48 | t=0.130 | 0.900 |
PCT, %, Mean±SD | 1.40 | 0.24±0.08 | 0.24±0.08 | t=−0.200 | 0.840 |
RDW, %, Mean±SD | 0.12 | 13.51±2.39 | 13.51±2.39 | t=−0.001 | 0.998 |
PT, s, Mean±SD | 1.12 | 11.25±1.01 | 11.26±1.01 | t=−0.010 | 0.993 |
APTT, s, Mean±SD | 1.12 | 26.76±4.17 | 26.76±4.17 | t=−0.001 | 0.996 |
TT, s, Mean±SD | 1.12 | 18.31±1.79 | 18.32±1.79 | t=−0.080 | 0.934 |
FIB, g/L, Mean±SD | 1.12 | 3.07±0.84 | 3.07±0.83 | t=0.030 | 0.973 |
D-dimer, mg/L, M (Q, Q) | 1.40 | 0.30 (0.17, 0.60) | 0.30 (0.17, 0.60) | Z=0.049 | 0.961 |
CEA, ng/mL, M (Q, Q) | 9.58 | 1.86 (0.90, 3.51) | 1.90 (0.91, 3.58) | Z=0.384 | 0.701 |
Carbohydrate antigen 199, U/mL, M (Q, Q) | 10.40 | 10.94 (6.80, 19.42) | 11.11 (6.92, 19.62) | Z=0.279 | 0.780 |
Carbohydrate antigen 125, U/mL, M (Q, Q) | 24.53 | 8.50 (5.90, 12.65) | 8.50 (6.30, 12.60) | Z=0.469 | 0.639 |
GPT, U/L, M (Q, Q) | 0.58 | 16.00 (11.30, 24.00) | 16.00 (11.60, 24.00) | Z=0.040 | 0.968 |
GOT, U/L, M (Q, Q) | 0.58 | 21.00 (17.00, 26.00) | 21.00 (17.00, 26.00) | Z=0.016 | 0.987 |
TBil, μmol/L, M (Q, Q) | 0.58 | 13.00 (9.25, 17.80) | 13.00 (9.20, 17.80) | Z=−0.035 | 0.972 |
ALB+GLB, g/L, Mean±SD | 0.58 | 66.61±7.48 | 66.62±7.49 | t=−0.010 | 0.989 |
ALB, g/L, Mean±SD | 0.58 | 41.63±4.90 | 41.63±4.91 | t=−0.030 | 0.977 |
GLB, g/L, Mean±SD | 0.58 | 24.99±4.56 | 24.99±4.56 | t=0.010 | 0.994 |
A/G, Mean±SD | 0.58 | 1.71±0.33 | 1.71±0.33 | t=−0.020 | 0.982 |
BUN, mmol/L, M (Q, Q) | 0.58 | 4.80 (3.80, 5.80) | 4.80 (3.80, 5.80) | Z=0.044 | 0.965 |
Cr, μmol/L, M (Q, Q) | 0.58 | 71.00 (61.00, 84.00) | 71.00 (61.00, 84.00) | Z=0.014 | 0.988 |
UA, μmol/L, M (Q, Q) | 1.12 | 288.00 (221.00, 359.00) | 288.00 (221.00, 359.00) | Z=−0.029 | 0.977 |
SD – standard deviation; M (Q1, Q3) – median (interquartile range); Hb – hemoglobin; RBC – red blood cell; WBC – white blood cell; NEUT – neutrophil; LYM – lymphocyte; MONO – monocyte; PLT – platelet; MPV – mean platelet volume; PCT – plateletcrit (the product of PLT and MPV); RDW – red blood cell distribution width; PT – prothrombin time; APTT – activated partial thromboplastin time; TT – thrombin time; FIB – fibrinogen; CEA – carcinoembryonic antigen; GPT – glutamic pyruvic transaminase; GOT – glutamic oxaloacetic transaminase; TBil – total bilirubin; ALB – albumin; GLB – globulin; A/G – ALB-to-GLB ratio; BUN – blood urea nitrogen; Cr – creatinine; UA – uric acid. |