04 February 2022: Clinical Research
Blood Pressure Rhythm and Blood Pressure Variability as Risk Factors for White Matter Lesions: A Cross-Sectional Study
Dong Zhang 1ABCDEF* , Mingli He 2ABCDG* , Qing He 1DEG* , Zeheng Li 3DEFDOI: 10.12659/MSM.933880
Med Sci Monit 2022; 28:e933880
Table 2 Main examination results of patients according to SBP day/night ratio quartile grouping.
| Variables | Group 1Q1–Q2 (−8.11–5.97) | Group 2Q3–Q4 (6.04–20.16) | P value |
|---|---|---|---|
| n | 66 | 66 | |
| 24hMSBP (mmHg, m±s) | 135.3±10.2 | 129.0±11.1 | 0.0012 |
| 24hMDBP (mmHg, m±s) | 79.4±7.2 | 76.8±6.8 | 0.0312 |
| DBPDNR (M, IQR) | 4.62 (−1.32–8.89) | 10.70 (7.79–14.20) | 1 |
| MDSBP (mmHg, m±s) | 135.6±10.3 | 133.6±10.9 | 0.2981 |
| MNSBP (mmHg, m±s) | 133.7±10.8 | 121.1±11.43 | 1 |
| MDDBP (mmHg, m±s) | 80.6±7.2 | 80.3±7.2 | 0.8461 |
| MNDBP (mmHg, m±s) | 77.2±7.3 | 71.5±7.2 | 2 |
| SBPCV (m±s) | 9.97±2.34 | 9.98±2.38 | 0.9792 |
| DBPCV (m±s) | 11.04±3.17 | 10.63±2.72 | 0.1991 |
| Fazekas score (m±s) | 2.62±1.74 | 1.53±1.52 | 1 |
| MSCBF (ml/100G/Min, m±s) | 36.52±9.83 | 45.92±13.82 | 0.0031 |
| MPCBF (ml/100G/Min, m±s) | 38.57±11.0 | 43.25±12.75 | 0.0021 |
| MoCA (M, IQR) | 18 (15–23) | 21 (17–24) | 0.0131 |
| 1 Man-Whitney test; 2 Independent sample -test; 3 Pearson Chi-square test; m – median; IQR – interquartile spacing; m±s – mean±standard deviation; MDSBP – daytime mean systolic blood pressure; MNSBP – mean systolic blood pressure at night; MDDBP – daytime mean diastolic blood pressure; MNDBP – mean diastolic pressure at night; SBPCV – coefficient of variation of 24-hour systolic blood pressure; DBPCV – 24-hour diastolic blood pressure variation coefficient; SBPDNR – systolic blood pressure difference ratio between day and night; DBPDNR: Diastolic blood pressure day/night difference ratio; MSCBF – bilateral mean subcortical local cerebral blood flow; MPCBF – bilateral mean paraventricular cerebral blood flow; MoCA – Monterey Cognitive Assessment Scale. | |||