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04 February 2022: Clinical Research

Blood Pressure Rhythm and Blood Pressure Variability as Risk Factors for White Matter Lesions: A Cross-Sectional Study

Dong Zhang 1ABCDEF* , Mingli He 2ABCDG* , Qing He 1DEG* , Zeheng Li 3DEF

DOI: 10.12659/MSM.933880

Med Sci Monit 2022; 28:e933880

Table 1 Baseline characteristics of patients according to SBP day/night ratio quartile grouping.

VariablesGroup 1Q1–Q2 (−8.11–5.97)Group 2Q3–Q4 (6.04–20.16)P value
n6666
Age (Year, M, IQR)70 (64–74)65 (61–72)0.0201
Male (n, %)33, 50.032, 48.50.8623
Culture above junior high school (n, %)29, 43.936, 54.50.3663
BMI (kg/m, m±s)24.77±4.0325.50±3.440.2622
Hypertension (n, %)60, 90.959, 89.40.7703
Dyslipidemia (n, %)19, 28.817, 25.80.6963
Diabetes (n, %)20, 30.317, 25.80.5613
Coronary heart disease (n, %)11, 16.713, 19.70.6523
Fasting blood glucose (mmol/L, M, IQR)5.39 (4.89–6.76)5.08 (4.71–6.14)0.1291
Smoke (n, %)12, 18.215, 22.70.5173
Drinking (n, %)17, 25.811, 16.70.2013
SBP on admission (mmHg, m±s)146.5±17.1143.7±18.60.3802
DBP on admission (mmHg, m±s)85.4±13.084.3±11.60.6061
Cholesterol (mmol/L, m±s)4.50±1.104.24±1.410.2412
Triglyceride (mmol/L, M, IQR)1.30 (1.04–1.79)1.08 (0.87–1.64)0.0841
LDL-C (mmol/L, m±s)2.44±0.692.34±0.870.4882
HDL-C (mmol/L, M, IQR)1.08 (0.96–1.29)1.02 (0.90–1.21)0.1061
1 Man-Whitney test;
2 Independent sample -test;
3 Pearson Chi-square test;
Q1-q4: CV is grouped according to the quartile of population; m – median; IQR – interquartile spacing; M±s – mean±standard deviation; LDL-C – low density lipoprotein cholesterol; HDL-C – high-density lipoprotein cholesterol.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750