01 March 1999
Value of non-invasive methods in assessment of adrenal function and bone status in asthma patients
Beata Kos-Kudła, Wojciech PluskiewiczMed Sci Monit 1999; 5(2): CR274-279 :: ID: 505131
Abstract
The aim of the study was to assess adrenal cortex function and skeletal status in female asthmatic patients. 26 women aged 44.8±9.9 years systemically treated with depot glucocorticoid (GC) and without GC-therapy were evaluated. Control group was formed of 19 healthy aged-matched women (mean age 41.8±7.4 years). The following endocrine tests were performed: short tetracosactrin ('Synacthen') test (SST) with salivary cortisol level measurement and 24-hour urinary excretion of free cortisol (UFC). Skeletal status was assessed using quantitative ultrasound of the heel. Speed of Sound (SOS) and Broadband Ultrasound Attenuation (BUA) were measured with Achilles (Lunar, USA). Suppression of adrenal function was observed in about half of patients with corticotherapy. Asthmatic patients not treated with glucocorticoids did not show alteration of adrenal function. Ultrasound values were significantly lower in asthma patients than in controls. Ultrasound parameters were lower in women with GC-therapy than in patients without use of GC, but the difference was significant only for SOS. The following SOS/BUA values were observed: in treated persons 1501.5±30.8/105.0±11.2, in not treated persons 1525.7±41.9/110.7±12.6, in controls 1545.0±32.1/120.4±7.7. Several instances of significant correlation between endocrinological and ultrasound values were noted in treated patients only (r=0.57-0.60, p
Keywords: quantitative ultrasound, skeletal status, adrenal function, Glucocorticoids, Asthma
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
18 Mar 2024 : Clinical Research
Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative StudyMed Sci Monit In Press; DOI: 10.12659/MSM.944136
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
Most Viewed Current Articles
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952