03 March 1997
Antioxidant status of patients with well controlled type I diabetes
Erika Szaleczky, József Prechl, Péter Pusztai, András Rosta, János Fehér, Anikó SomogyiMed Sci Monit 1997; 3(2): CR163-166 :: ID: 500677
Abstract
17 non-diabetic subjects and 11 patiens with type I diabets - matched in age and BMI -were studied in order to evaluate the effects of well controlled diabets on antioxidant status. Mean duration of diabets was 10 years; a mean HbA1c value of 6 .06 -0.48% implied a good blood glucose control. All the diabetics subjects were on intensive insulin therapy and had no renal complications. Atherogen index (total cholesterol/HDL cholesterol) was practically identical in the two groups (3.05 vs 156 µM), but the difference was not significant (p=0.11). Antioxidant enzyme activities (erythrocyte superoxide dismutase and catalase, whole blood glutahione peroxidase) did not differ in the two groups. Similarly Total Antioxidant Status - a measure of overall antioxidant defense in plasma - and TBARS concentrations were not statistically different in controls and diabetics.We assume that type I diabets, when blood glucose is stictly controlled by intensive insulin therapy, is not accompanied by changes in the prooxidant - antioxidant balance.
Keywords: Diabetes Mellitus, intensive insulin therapy, Lipid Peroxides, antioxides, glutaxione peroxidase, total antioxidant status
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
18 Mar 2024 : Clinical Research
Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative StudyMed Sci Monit In Press; DOI: 10.12659/MSM.944136
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
Most Viewed Current Articles
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952